MUMBAI, India, June 19 -- Intellectual Property India has published a patent application (202617058727 A) filed by Astrazeneca Ab on May 08, 2026, for T Cell Binding Compositions And Methods.
Inventors include Cobbold, Mark; Cayatte, Corinne; Ciucci, Thomas; Mazor, Yariv; Cemerski, Saso; Dovedi, Simon; Lloyd, Christopher; Seaman, Jonathan; Lisiero, Dominique; Zhang, Hanzhi; Du, Qun; Creigh-Pulatmen, Tilbe; Kaplan, Gilad; Bergamaschi, Cristina; Li, Xiuling; Fu, Ying; Lee, Amber; Sandercock, Alan; Chennupati, Vijay; Payne, Sterling; Lara, Abigail Bowlsbey; Castan, Laure; Sermadiras, Isabelle; Vickery, Owen; Sitnikova, Suzanne; and Walseng, Even.
The application for the patent was published on June 05, 2026, under issue no. 23/2026.
Abstract: The disclosure generally relates to binding proteins that comprise antigen binding sites, a T cell receptor binding site, and a T cell co-stimulatory molecule binding site. The disclosure also relates to pharmaceutical compositions comprising such binding proteins, nucleic acid molecules encoding such binding proteins, and vectors comprising such nucleic acid molecules. The disclosure further relates to methods of treating a disorder or condition using such binding proteins and pharmaceutical compositions, binding proteins and pharmaceutical compositions for use in the treatment of a disorder or condition, and the use of such binding proteins and pharmaceutical compositions for the manufacture of a medicament for treating a disorder or condition.
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