MUMBAI, India, June 24 -- Intellectual Property India has published a patent application (202431097118 A) filed by Indian Institute Of Technology, Guwahati on December 09, 2024, for System And Method For Dynamic Modulation Of Illumination Beam Intensity In Stochastic Optical Reconstruction Microscopy.
Inventors include Bosanta Ranjan Boruah; Anupam Bharadwaj; Amalesh Kumar; and Bithiah G Jaganathan.
The application for the patent was published on June 12, 2026, under issue no. 24/2026.
Abstract: ABSTRACT “SYSTEM AND METHOD FOR DYNAMIC MODULATION OF ILLUMINATION BEAM INTENSITY IN STOCHASTIC OPTICAL RECONSTRUCTION MICROSCOPY” The present invention provides a system (100) for dynamic modulation of illumination beam spatial intensity profile in stochastic optical reconstruction microscopy comprising a laser source (1), a light modulator (13), and a camera (20). The laser source (1) emits the light beam onto said light modulator (13) that sequentially displays a hologram pattern selected by user defined region of interest and dynamically modulates the light beam to reflect the pattern that is to be focused on a sample plane (18) to form an image on said camera (20). A method for dynamic modulation of illumination beam spatial intensity profile in a stochastic optical reconstruction microscope comprising step of focusing a light beam from a laser source (1) onto a light modulator (13) where a user defined hologram pattern is present to obtain a diffracted beam and creating a user defined illumination pattern on the specimen of the sample plane (18) to excite the specimen and form an image on said camera (20). Figure 1 on sheet no. 1 of the drawings may accompany the abstract when published.
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