MUMBAI, India, Aug. 17 -- Intellectual Property India has published a patent application (202541010274 A) filed by Vaidhyanathan Baskaran; Dhivya Dharshini Udhaya Kumar; Girish Kumar Kaliappan; Janarthanan Karuppusamy; and Ramanan Kandasamy Balaji on February 07, 2025, for Synthesis Of Zinc Whitlockite For Bone Regeneration.
Inventors include Vaidhyanathan Baskaran; Dhivya Dharshini Udhaya Kumar; Girish Kumar Kaliappan; Janarthanan Karuppusamy; and Ramanan Kandasamy Balaji.
The application for the patent was published on August 14, 2026, under issue no. 33/2026.
Abstract: 8.ABSTRACT OF THE INVENTION: This research investigates the synthesis of zinc-containing whitlockite (Cal0Zn!OH2(P04)i4), a promising material for biodegradable orthopedic implants. The compound was successfully prepared at room temperature through a chemical reaction involving calcium nitrate, zinc nitrate, and ammonium hydrogen phosphate at a pH of approximately 11.0. The X~ray diffraction pattern of the synthesized compound matched that of magnesium-iron whitlockite (Cal8(Mg,Fe)2H2(P04)14), a mineral related to tricalcium phosphate. Zinc incorporation into whitlockite enhances the material's biocompatibility, supporting osteogenesis and potentially promoting bone regeneration.The ability to incorporate zinc into the whitlockite structure offers additional benefits compared to traditional calcium phosphate materials, such as hydroxyapatite, which is commonly used in bone grafts. Zinc is known to improve cellular functions, including enhancing the activity of osteoblasts, which could lead to better bone integration and healing.The zinc-containing whitlockite compound can be used alone or as an additive to hydroxyapatite in orthopedic implants, offering a biodegradable and biocompatible alternative. The findings lay the groundwork for further research into the use of zinc-doped whitlockite for bone regeneration and its potential as a material for future orthopedic_applications. Keywords: Zinc-containing whitlockite, biodegradable implants, hydroxyapatite, calcium phosphate, biocompatibility.
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