MUMBAI, India, June 30 -- Intellectual Property India has published a patent application (202641075858 A) filed by Paavai Engineering College; Mr P. Elanchezhian; and Mr. Mds. Rajaruban on June 18, 2026, for Sustainable Biofilm Production Using Sago Industry Effluent And Vegetable Peels To Improve Fruit Shelf Life.
Inventors include Ms. S. Reshma; Ms. Shifana Muhammed; Ms. S. Sivasankari; and Ms. M. Dakshayani.
The application for the patent was published on June 26, 2026, under issue no. 26/2026.
Abstract: A fast-dissolving bio film for anti-urolithiatic application and a method for its preparation and in-vitro evaluation are disclosed. Urolithiasis, and in particular the formation of struvite stones composed of magnesium ammonium phosphate hexahydrate, is a prevalent and recurrent disorder of the urinary tract that is difficult to manage by conventional means and that creates a need for safe and non-invasive preventive therapies. The invention exploits the synergism between four medicinal plants, namely Abutilon indicum, Cocos nucifera, Datura stramonium, and Piper betel, the leaves of which are shade-dried, comminuted, and subjected to Soxhlet extraction using ethanol to recover their phytoconstituents. The extract is combined with a substantially natural film-forming matrix comprising guar gum as the film- forming polymer, glycerin as the plasticiser and humectant, palm sugar as the sweetener, and citric acid as an acidulant, and the resulting solution is cast by the solvent- casting technique and dried to yield a coherent fast-dissolving bio film that affords improved bioavailability of the phytoconstituents and improved patient compliance. The anti-urolithiatic potential of the film is assessed in vitro by the single-diffusion gel-growth technique, in which struvite crystals are grown in an acidified sodium metasilicate gel under simulated urinary conditions and the percentage of inhibition is determined from the reduction in the number, size, and mass of the harvested crystals upon addition of graded concentrations of the extract. The films exhibit delayed nucleation and a marked, concentration-dependent reduction in struvite crystal growth, with a percentage of inhibition exceeding eighty per cent at a five per cent extract concentration, and a comparable order of efficiency is observed across formulations of differing composition, thereby establishing the bio film of the invention as a promising preventive and therapeutic option for the management of struvite urolithiasis.
Disclaimer: Curated by HT Syndication.
