MUMBAI, India, June 30 -- Intellectual Property India has published a patent application (202418003874 A) filed by Bantam Pharmaceutical, LLC on January 19, 2024, for Substituted Pyrazole Compounds And Methods Of Using Them For Treatment Of Hyperproliferative Diseases.

Inventors include Siddiqui, Arshad, M.; Ciblat, Stephane; Dery, Martin; Constantineua-Forget, Lea; Grand-Maitre, Chantal; Bruneau-Latour, Nicolas; Shipps, Gerald, W.; Cooper, Alan, B.; Oza, Vibha Filed On; Kostura, Matthew, W.; Luther, Michael; and Levine, Jedd.

The application for the patent was published on June 26, 2026, under issue no. 26/2026.

Abstract: Disclosed are compounds useful, for example, in methods of treating hyperproliferative disorders such as cancer, methods of arresting the cell cycle in cancer cells, methods of inhibiting glutathione synthesis in cancer cells, and associated compounds for use and uses in medicaments. In certain embodiments, the methods, uses and compounds are provided with reference to compounds of the structural formulae (Ia), (Ib), (Ic), (Id) and (Ie), in which R1, L1, L2, Q, L3, R3, L4, R4, L5, and R5 are as described herein. In certain embodiments, compounds disclosed herein are especially active against cancers having a mutant KRAS gene.

Disclaimer: Curated by HT Syndication.