MUMBAI, India, Oct. 12 -- Intellectual Property India has published a patent application (202621097593 A) filed by Prof. Dr. Nilesh Shantaram Pawar; Rajashri Pachpande; Dr. Pundalik P. Mali; Ganesh Wagh; Vivek R. Patil; Pandharinath Lande; and Sachin Bhogade on August 12, 2026, for Substituted Ciprofloxacin-Based Quinolone Compounds As Antibacterial Agents.
Inventors include Prof. Dr. Nilesh Shantaram Pawar; Rajashri Pachpande; Dr. Pundalik P. Mali; Ganesh Wagh; Vivek R. Patil; Pandharinath Lande; and Sachin Bhogade.
The application for the patent was published on October 09, 2026, under issue no. 41/2026.
Abstract: ABSTRACT SUBSTITUTED CIPROFLOXACIN-BASED QUINOLONE COMPOUNDS AS ANTIBACTERIAL AGENTS 5 10 15 20 25 The present invention relates to substituted ciprofloxacin compounds, methods for their preparation, and their antimicrobial applications. The invention provides a simple, cost-effective, scalable, and industry-feasible method for synthesizing ciprofloxacin derivatives through substitution at the piperazinyl moiety, including N-acyl, N-alkyl, N- aryl, Amide, Mannich bases and Schiff bases. The synthesized compounds exhibit enhanced antibacterial and anti-MRSA activity compared to the parent ciprofloxacin. These substituted ciprofloxacin compounds are intended for use as effective antimicrobial agents, particularly against bacterial and MRSA infections.
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