MUMBAI, India, Sept. 14 -- Intellectual Property India has published a patent application (202641098435 A) filed by S. Nandhakumar; S. Sadana Shree; K. Gokulkumar; S. Priyadharshini; and N. Harikrishinan on August 14, 2026, for Shape Memory Drug-Releasing Electrospun Polymeric Matrix For Minimally Invasive Bone Regeneration.
Inventors include S. Nandhakumar; S. Sadana Shree; K. Gokulkumar; S. Priyadharshini; and N. Harikrishinan.
The application for the patent was published on September 11, 2026, under issue no. 37/2026.
Abstract: Abstract: The present invention relates to a shape memory drug-releasing electrospun polymeric matrix for minimally invasive bone regeneration. The invention provides a biodegradable electrospun nanofibrous scaffold capable of temporary deformation into a compact configuration, fixation of the temporary shape, and recovery of its predetermined geometry upon exposure to a physiological stimulus, thereby facilitating minimally invasive implantation and effective conformity to irregular bone defects. The polymeric matrix is adapted to incorporate one or more pharmaceutically acceptable therapeutic agents and provides controlled and sustained localized release to promote bone tissue regeneration while miiniiirns-yErmic-A rki .The scaffo1d5 s istihjECCedrao chefnicat:ititisslinking . and thermal shape programming to impart shape-memory characteristics and maintain structural integrity during implantation and recovery. The electrospun polymeric matrix possesses a porous architecture resembling the native extracellular matrix, thereby supporting tissue regeneration and temporary mechanical support at the defect site. The invention provides a simple, reproducible, and scalable biodegradable scaffold suitable for bone tissue engineering and regenerative medicine applications. Simultaneously, the scaffold provides controlled and sustained release of the incorporated therapeutic agent, thereby promoting localized bone regeneration. The invention provides a simple, reproducible, and scalable process for fabricating a biodegradable shape-memory electrospun polymeric matrix suitable for bone tissue engineering applications.
Disclaimer: Curated by HT Syndication.
