MUMBAI, India, July 31 -- Intellectual Property India has published a patent application (202411096012 A) filed by Lovely Professional University on December 05, 2024, for Rice-Based Oral Soluble Films For Exemestane Delivery In Breast Cancer Treatment.
Inventors include Poluri Koteswari; Paschal Chukwuemeka; and Abdel Malik Ahmad.
The application for the patent was published on July 24, 2026, under issue no. 30/2026.
Abstract: The present invention relates to the technical field of pharmaceutical delivery systems, specifically to an oral soluble film designed for the delivery of exemestane in breast cancer treatment. The invention comprises a film matrix formed primarily from rice protein and starch, which are selected for their digestibility, biodegradability, and non-immunogenic properties. These components are mixed in specific ratios to create a cohesive matrix that encapsulates exemestane, the active pharmaceutical ingredient. The film matrix is further enhanced with organoleptic additives for taste masking, preservatives for microbial stability, and plasticizers to improve flexibility and handling. The film is configured to dissolve in the oral cavity, facilitating direct absorption of exemestane through mucosal tissues and potentially bypassing the P- glycoprotein efflux mechanism in the gastrointestinal tract. The invention includes a method for preparing an oral soluble film by creating a homogenous film-forming solution, casting, drying, and evaluating its physicochemical properties, drug release, and bioavailability. Dated this …. Day of November, 2024 Dr. Monica Gulati Registrar Lovely Professional University
Disclaimer: Curated by HT Syndication.
