MUMBAI, India, Sept. 22 -- Intellectual Property India has published a patent application (202521079928 A) filed by Indian Institute Of Technology Gandhinagar on August 22, 2025, for Pyrazole-Based Derivatives And A Process For Their Preparation.

Inventors include Kirubakaran Sivapriya; Somasundaram Kumar; and Mukherjee Arani.

The application for the patent was published on September 18, 2026, under issue no. 38/2026.

Abstract: ABSTRACT PYRAZOLE-BASED DERIVATIVES AND A PROCESS FOR THEIR PREPARATION The present disclosure relates to pyrazole-based derivatives and a process for their preparation. Particularly, the present disclosure relates to pyrazole-based derivatives as ß-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors for cancer therapy. Further, the pyrazole-based derivatives have improved metabolic safety, target specificity and blood-brain barrier penetration. Furthermore, the present disclosure provides a process for the preparation of the pyrazole-based derivatives. The process of the present disclosure is simple, efficient, cost-effective, environment-friendly and commercially scalable.

Disclaimer: Curated by HT Syndication.