MUMBAI, India, Sept. 7 -- Intellectual Property India has published a patent application (202617082254 A) filed by Jsr Corporation on July 03, 2026, for Production Method For Chromatographic Carrier.
Inventors include Miyajima, Ken; Akiyama, Minato; Matsumoto, Kentarou; and Kobayashi, Kunihiko.
The application for the patent was published on September 04, 2026, under issue no. 36/2026.
Abstract: The present invention provides a method for easily producing a chromatographic carrier that has a high dynamic binding capacity to antibodies or fragments thereof, inhibits the leakage of protein ligands during isolation, and inhibits the aggregation of carriers. Provided is a production method for a chromatographic carrier comprising the ligand binding step, ligand-bound carrier bed forming step, ligand-bound carrier flushing and cleaning step, and ligand-bound carrier stirring and cleaning step described hereafter. Ligand binding step: a step in which a protein ligand is bound to a solid phase carrier. Ligand-bound carrier bed forming step: a step in which a container is filled with the ligand-bound carrier obtained in the ligand binding step to form a ligand-bound carrier bed. Ligand-bound carrier flushing and cleaning step: a step in which the ligand-bound carrier bed formed in the ligand-bound carrier bed forming step is cleaned one or more times by flushing the bed with a cleaning liquid. Ligand-bound carrier stirring and cleaning step: a step in which the ligand-bound carrier after the ligand-bound carrier flushing and cleaning step is cleaned one or more times by stirring in a cleaning liquid.
Disclaimer: Curated by HT Syndication.
