MUMBAI, India, Sept. 7 -- Intellectual Property India has published a patent application (202617082165 A) filed by Jsr Corporation on July 03, 2026, for Production Method For Chromatographic Carrier.
Inventors include Miyajima, Ken; Akiyama, Minato; Matsumoto, Kentarou; and Kobayashi, Kunihiko.
The application for the patent was published on September 04, 2026, under issue no. 36/2026.
Abstract: The present invention provides a method for easily producing a chromatographic carrier that has a high dynamic binding capacity to antibodies or fragments thereof, inhibits the leakage of protein ligands during isolation, and inhibits the aggregation of carriers. Provided is a production method for a chromatographic carrier comprising the solid phase carrier cleaning step, ligand binding step, and ligand-bound carrier cleaning step described hereafter. Solid phase carrier cleaning step: a step in which a solid phase carrier is cleaned using at least one cleaning liquid selected from cleaning liquids containing hydrogen peroxide, cleaning liquids containing peracetic acid, and cleaning liquids (other than cleaning liquids containing hydrogen peroxide and cleaning liquids containing peracetic acid) having a pH of 0-3 or a pH of higher than 12.5 to 14, and the surface of the solid phase carrier is made hydrophilic. Ligand binding step: a step in which a protein ligand is bound to the solid phase carrier cleaned in the solid phase carrier cleaning step. Ligand-bound carrier cleaning step: a step in which the carrier obtained in the ligand binding step is cleaned.
Disclaimer: Curated by HT Syndication.
