MUMBAI, India, June 26 -- Intellectual Property India has published a patent application (202331055247 A) filed by Kalinga Institute Of Industrial Technology Deemed To Be University; and Kalinga Renewable Energy Manufacturers Private Limited on August 17, 2023, for Process For Inhibiting Intein Splicing By Nanoparticle And Use Thereof.
Inventors include Sasmita Nayak; Deepak Kumar Ojha; Ananya Nanda; Sourya Subhra Nasker; and Ashwaria Mehra.
The application for the patent was published on June 19, 2026, under issue no. 25/2026.
Abstract: The present invention provides a method for inhibiting intein splicing in a precursor protein, the method comprising; taking the precursor protein in a buffer and TCEP- HCl to obtain a mixture; adding ZnO nanoparticles to the mixture and allowing to react for a period in the range of 4 -6 hours; stopping the reaction by addition of a loading dye; and observing results of the reaction by an electrophoresis method, wherein accumulation of the precursor protein and reduction of splicing and N-terminal cleavage products confirm the inhibition of intein splicing in the precursor protein.
Disclaimer: Curated by HT Syndication.
