MUMBAI, India, Sept. 22 -- Intellectual Property India has published a patent application (202517017650 A) filed by Singh, Pawan Kumar; Singh, Sarita; Gaikwad, Vaishali Hanmantrao; and Gaikwad, Hanmantrao Ramdas on February 28, 2025, for Polyherbal Compounds For Managing Hypertension And Related Disorders.
Inventors include Singh, Pawan Kumar; Singh, Sarita; Gaikwad, Vaishali Hanmantrao; and Gaikwad, Hanmantrao Ramdas.
The application for the patent was published on September 18, 2026, under issue no. 38/2026.
Abstract: The present invention relates to a polyherbal compound based formulation for managing hypertension and related disorders, comprising Dioscin, Withanolide A, Withaferin A, Withanolide D, P-Sitosterol, Diosgenin, Arjunolic Acid, Caffeic Acid, and Kaempferol. The compounds targets multiple mechanistic pathways in hypertension, including the Renin- Angiotensin-Aldosterone System (RAAS), Sympathetic Nervous System, Vascular Resistance, Nitric Oxide, and Stress-Responsive pathways. It offers a comprehensive and synergistic approach for improving vascular health, reducing blood pressure, regulating the levels of HDL and lowering of Cholesterol, LDL and Triglycerides. The compound/s is formulated for enhanced bioavailability and efficacy, and can be used as an adjuvant with antihypertensive agents. The invention also includes methods for extracting, purifying, and standardizing the active ingredients, ensuring consistent quality. The compounds is suitable for managing hypertension, cardiovascular diseases, metabolic disorders, and stress. It can be administered in various dosage forms such as tablets, capsules, syrups, and powders.
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