MUMBAI, India, Sept. 22 -- Intellectual Property India has published a patent application (202647108772 A) filed by Otsuka Pharmaceutical Co. , Ltd. on September 10, 2026, for Piperidine- And Morpholine-Carboxylate Compounds As Sort1 Inhibitors.
Inventors include Uematsu, Mika; Woolford, Alison Jo-Anne; Tamai, Taichi; Norton, David; Iwata, Shin; Mortenson, Paul Neil; Yamauchi, Takahito; Tamanini, Emiliano; Ishikawa, Shumpei; Liebeschuetz, John Walter; Matsumura, Chiharu; Chessari, Gianni; Takahashi, Haruka; Walton, Hugh Patrick Charles; Tanaka, Hirotaka; Cons, Benjamin David; Yamaguchi, Atsushi; Wilsher, Nicola Elizabeth; Chiba, Takuya; Walsh, Louise Marie; Miyamoto, Motoyuki; Johnson, Christopher Norbert; Kishi, Junichiro; Day, James Edward Harvey; Suzuki, Masaki; Osborne, James Daniel; Nagase, Tsuyoshi; St. Denis, Jeffrey David; Lindovska, Petra; Ward, Stuart Iain; and Baker-Glenn, Charles Anthony Graham.
The application for the patent was published on September 18, 2026, under issue no. 38/2026.
Abstract: Disclosed are compounds, or salts thereof, with sortilin-binding inhibitory activity, medical use thereof for treating, preventing, and/or diagnosing diseases associated with sortilin ligands, and methods of preparing said compounds, or salts thereof. Provided is a compound of formula (I), or a salt thereof, wherein R1 is H, etc.; R2 is optionally substituted C1-6 alkyl, etc.; R3 is CH2 or O; R4 is H or C1-6 alkyl; and Ring A is optionally substituted partially unsaturated or unsaturated 7- to 15- membered bicyclic or tricyclic heterocyclyl.
Disclaimer: Curated by HT Syndication.
