Intellectual Property India Publishes Patent Application for Phosphate Salt Of 1-((3s,4r)-3-((2-((1-Ethyl-1h-Pyrazol-4-Yl)amino)-7h-Pyrrolo[2,3-D]pyrimidin-4-Yl)oxy)- 4-Fluoropiperidin-1-Yl)prop-2-En-1-One, Crystalline Form Thereof, And Method For Preparation Thereof

MUMBAI, India, July 31 -- Intellectual Property India has published a patent application (202617069177 A) filed by Daewoong Pharmaceutical Co. , Ltd. on June 02, 2026, for Phosphate Salt Of 1-((3s,4r)-3-((2-((1-Ethyl-1h-Pyrazol-4-Yl)amino)-7h-Pyrrolo[2,3-D]pyrimidin-4-Yl)oxy)- 4-Fluoropiperidin-1-Yl)prop-2-En-1-One, Crystalline Form Thereof, And Method For Preparation Thereof.

Inventors include Park, Joon Seok; Hyun, Hyae Jung; Lee, Joon-Hwan; Jun, Sun Ah; Kim, Namyoun; Kim, Wonsun; and Kim, Cheolwoong.

The application for the patent was published on July 24, 2026, under issue no. 30/2026.

Abstract: The present invention relates to a phosphate salt of 1-((3S,4R)-3-((2-((1-ethyl-1H-pyrazol-4-yl)amino)-7H-pyrrolo[2,3-d] pyrimidin-4-yl)oxy)-4-fluoropiperidin-1- yl)prop-2-en-1-one, a crystalline form thereof, and a method for preparing same. The phosphate salt and the crystalline form have low hygroscopicity and improved stability and solubility, compared to free bases, and thus are suitable for pharmaceutical use. Also, the method for preparing the phosphate or crystalline form, of the present invention, has the advantages of enabling mass production and improving the safety of preparation processes by using a safe material compared to reactants used in conventional preparation methods.

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