MUMBAI, India, Oct. 26 -- Intellectual Property India has published a patent application (202611106903 A) filed by Panipat Institute Of Engineering And Technology Piet on September 04, 2026, for Pharmaceutical Composition Comprising A Phase-Separating Film-Forming Gel Matrix For Controlled Topical Drug Delivery.
Inventors include Dr. Parveen Kumar Goyal; Dr. Kavita Sangwan; and Mr. Rahul Singla.
The application for the patent was published on October 23, 2026, under issue no. 43/2026.
Abstract: [068] The present invention relates to a pharmaceutical composition comprising a phase-separating film-forming gel matrix for controlled topical drug delivery. The composition comprises at least one therapeutically active agent, at least one film-forming polymer, at least one volatile carrier, and at least one phase-separation regulating component and is configured to remain substantially uniform and spreadable before application. Following application onto a biological surface, progressive loss of the volatile carrier alters compatibility among components and induces controlled phase separation while the film-forming polymer generates an adherent residual film. The resulting film comprises a polymer-rich structural phase and a drug-enriched delivery phase comprising discrete or interconnected microdomains capable of acting as internal drug reservoirs and transport pathways. The phase-separation regulating component can maintain the therapeutic agent in a release- available state and reduce uncontrolled crystallization during film formation. The microstructured film thereby provides improved residence, controlled drug partitioning and release, reduced transfer, and sustained availability of therapeutic agent at the biological surface without requiring a preformed patch structure. Accompanied Drawing [FIGS. 1-2]
Disclaimer: Curated by HT Syndication.
