MUMBAI, India, June 19 -- Intellectual Property India has published a patent application (202617056691 A) filed by Uniqure Biopharma B. V. on May 04, 2026, for Nucleic Acid Regulation Of Msh3 In Repeat Expansion Disorders.
Inventors include Van Der Bent, Melanie Leontien; and Valles Snchez, Astrid.
The application for the patent was published on June 05, 2026, under issue no. 23/2026.
Abstract: The present invention relates to nucleic acid molecules comprising nucleotide sequences encoding two or more RNAs, wherein at least one RNA comprises a guide sequence substantially complementary to a region within MutS Homolog 3 (MSH3) gene. The invention also relates to recombinant adeno-associated viral (rAAV) vectors, pharmaceutical compositions comprising such rAAV vectors, and their uses in the treatment of repeat expansion disorders.
Disclaimer: Curated by HT Syndication.
