MUMBAI, India, Sept. 28 -- Intellectual Property India has published a patent application (202647112219 A) filed by Bayspair Inc. on September 18, 2026, for Nuclease System For Genome Editing.
Inventor includes Ikeda, Kazuya.
The application for the patent was published on September 25, 2026, under issue no. 39/2026.
Abstract: The present invention provides a chimeric nucleic acid-guided nuclease including at least one domain substituted with distinct bacterial species. These chimeric nucleases improve function of modified guide polynucleotides, enhancing the genomic modification abilities of nucleic acid-guided nucleases. CRISPR-Cas systems such as those described herein are often used in genome editing, but the complexity of the polypeptides and polynucleotides leads to unpredictable outcomes. The chimeric CRISPR-Cas system disclosed herein was surprisingly able to rescue function of a previously non-functional guide nucleotide. The nucleases and methods described herein are useful for treating diseases associated with a gene or polynucleotide.
Disclaimer: Curated by HT Syndication.
