MUMBAI, India, Sept. 22 -- Intellectual Property India has published a patent application (202647109140 A) filed by Christian-Albrechts-Universitt Zu Kiel on September 11, 2026, for Novel Bioartificial Vascular Grafts And Methods For Their Fabrication.
Inventors include Berndt, Rouven; Zitta, Karina; Pfarr, Julian; and Albrecht, Martin.
The application for the patent was published on September 18, 2026, under issue no. 38/2026.
Abstract: The present invention relates to a novel bio-ink for preparing bioartificial vascular grafts which are highly useful for vascular and cardiovascular research and therapy, and in particular for surgical vascular and cardiovascular repair and bypass surgery. The bio-ink composition of the invention comprises a peptide-grafted alginate and smooth muscle cells, endothelial cells or cells which are capable of developing into endothelial cells. According to the invention, the peptides grafted onto the alginate are derived from an extracellular matrix protein or mimic such proteins. The invention also relates to a method for manufacturing a bioartificial vascular graft comprising the printing of the bio-ink composition of the invention. Bioartificial vascular grafts, which are obtainable by the method of the invention, are also encompassed by the invention. In yet another aspect, the invention relates to the use of the bio-ink for in vitro drug screening and as an in-vitro training model for endovascular or surgical training.
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