MUMBAI, India, Sept. 22 -- Intellectual Property India has published a patent application (202641106001 A) filed by Saveetha Institute Of Medical And Technical Sciences on September 03, 2026, for Non-Invasive Blood Glucose Monitoring Based On Transmittance And Refraction Of Visible Laser Light.
Inventors include N V Santhosh; Dr. Arangasamy R; Dr. Josh Kumar; and Dr Ramya Mohan.
The application for the patent was published on September 18, 2026, under issue no. 38/2026.
Abstract: Non-invasive blood glucose monitoring has emerged as a promising alternative to conventional invasive methods that require finger-pricking and test strips, which can cause discomfort, risk of infection, and reduced patient compliance. This study presents a novel approach for non-invasive glucose measurement based on the transmittance and refraction properties of visible laser light. A low-power visible laser, typically in the red wavelength range, is directed through a biological tissue such as a fingertip. As the laser light interacts with blood and interstitial fluids, variations in glucose concentration influence the optical properties of the medium, leading to measurable changes in light intensity and refraction patterns. The proposed system consists of a laser source, optical interaction medium, photodiode sensor, and signal conditioning circuitry. The transmitted and refracted light signals are captured by the photodiode and converted into electrical signals, which are then amplified and filtered to reduce noise and improve accuracy. By analyzing the variations in signal intensity and refractive behavior, the system estimates glucose concentration using calibrated mathematical models. This method leverages the relationship between glucose levels and changes in optical density and refractive index, enabling continuous and painless monitoring without the need for chemical reagents or invasive sampling. While environmental factors, tissue variability, and calibration challenges may affect accuracy, the results indicate strong potential for further development. This non-invasive technique offers advantages such as ease of use, cost-effectiveness, and improved patient comfort, making it suitable for frequent monitoring and long-term diabetes management. Future work will focus on enhancing precision, integrating digital processing techniques, and validating the system across diverse populations to achieve clinical reliability.
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