MUMBAI, India, Oct. 5 -- Intellectual Property India has published a patent application (202647114755 A) filed by Zymeworks Bc Inc. on September 25, 2026, for Multispecific And Costimulatory Antibody Constructs And Methods Of Use Thereof.
Inventors include Spreter Von Kreudenstein, Thomas; Weisser, Nina E.; Piscitelli, Chayne L.; Newhook, Lisa; Lau, Desmond Ka Wing; Repenning, Peter; Desjardins, Genevive; Afacan, Nicole; Canals Hernaez, Diana; Bhojane, Purva Prashant; Escalante, Nichole K.; and Perez Escanda, Diego.
The application for the patent was published on October 02, 2026, under issue no. 40/2026.
Abstract: The present disclosure describes costimulatory multivalent and multispecific antibody constructs capable of binding at least two different antigens on a cytotoxic effector cell and at least one disease-associated antigen (e.g., a TAA) on a target cell. Pharmaceutical compositions comprising such antibody constructs and methods of preparing and using such constructs and compositions, e.g., for the treatment of a disease such as cancer, are also disclosed.
Disclaimer: Curated by HT Syndication.
