MUMBAI, India, Oct. 26 -- Intellectual Property India has published a patent application (202611106810 A) filed by Panipat Institute Of Engineering And Technology Piet on September 04, 2026, for Mucoadhesive Controlled-Release Pharmaceutical Lozenge With Dissolution-Modulating Matrix.
Inventors include Dr. Parveen Kumar Goyal; and Ms. Sakshi Garg.
The application for the patent was published on October 23, 2026, under issue no. 43/2026.
Abstract: 064] The present invention relates to a mucoadhesive controlled-release pharmaceutical lozenge comprising at least one pharmaceutically active ingredient, at least one mucoadhesive polymer, at least one dissolution modifier, and a pharmaceutically acceptable matrix-forming excipient. Upon exposure to saliva, the lozenge develops a hydration-responsive matrix comprising a hydrated mucoadhesive region and a diffusion-regulating region while retaining a comparatively less-hydrated internal matrix region. The dissolution modifier regulates saliva penetration, polymer hydration, matrix dissolution and/or transport of the active ingredient, while progressive hydration and erosion provide a dynamically changing release interface. The coordinated action of mucoadhesion, diffusion regulation, dissolution, and matrix erosion reduces uncontrolled initial release and enables prolonged delivery of the active ingredient within the oral cavity. The lozenge may be configured for local oral action or mucosal delivery and may be manufactured as a substantially unitary matrix dosage form. Accompanied Drawing [FIGS. 1-2]
Disclaimer: Curated by HT Syndication.
