MUMBAI, India, Sept. 22 -- Intellectual Property India has published a patent application (202641106481 A) filed by Marri Laxman Reddy Institute Of Pharmacy on September 03, 2026, for Moringa Oleifera Bilayer Mucoadhesive Buccal Film For Gastroprotective Transmucosal Delivery.
Inventors include Dr. Suvendu Saha; N. Akshitha; M. Swathi; P. Shiva Prasad; M. Akshaya; Dr. Arunabha Mallik; Dr. Saikat Das; and Dr. Akula Sowjanya.
The application for the patent was published on September 18, 2026, under issue no. 38/2026.
Abstract: The invention provides a bilayer mucoadhesive buccal film containing an extract from Moringa oleifera leaves. The film comprises a mucosa-contacting layer (103) containing HPMC E15, Carbopol 934P, PEG 400, and propylene glycol, and an ethyl-cellulose backing layer (102) on the oral-cavity side. The film is prepared by solvent casting and cut into 2 cm × 2 cm units, each containing 50 mg or 100 mg of extract equivalents. The leaf extract is prepared by maceration with 70% ethanol at a 1:5 w/v ratio for 72 hours. In an aspirin-induced gastric-ulcer model, the 50 mg and 100 mg film groups showed 71.43% and 89.29% ulcer inhibition, respectively, compared with 57.74% for the tested free extract. Histopathology supported gastric mucosal protection. The multilayer architecture provides a defined platform for directional buccal delivery of Moringa oleifera extract.
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