MUMBAI, India, July 24 -- Intellectual Property India has published a patent application (202418069351 A) filed by Precigen, Inc. on September 13, 2024, for Modulating Expression Of Polypeptides Via New Gene Switch Expression Systems.
Inventors include Shah, Rutul R.; Reed, Thomas D.; and Bolinger, Cheryl G..
The application for the patent was published on July 17, 2026, under issue no. 29/2026.
Abstract: Disclosed herein are polynucleotides encoding ligand-inducible gene switch polypeptides, and systems comprising gene switch polypeptides for modulating the expression of a heterologous gene and an interleukin in a host cell. The compositions, methods and systems described herein facilitate ligand dependent expression of polypeptides including but not limited to cytokines and antigen binding polypeptides.
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