MUMBAI, India, July 13 -- Intellectual Property India has published a patent application (202621060294 A) filed by Svkm'S Nmims School Of Pharmacy And Technology Management Shirpur on May 12, 2026, for Modified Polymer Conjugate For Targeted Cancer Delivery And Method Of Synthesis Thereof.
Inventors include Dr Mayank Sharma; Dr Devendra Kumar; and Mr Shubhankar Bera.
The application for the patent was published on July 10, 2026, under issue no. 28/2026.
Abstract: The present disclosure provides a modified polymer conjugate for targeted cancer delivery comprising folic acid conjugated with phenylalanine through an amide bond to form a phenylalanine-modified folic acid, and methoxy polyethylene glycol conjugated to the phenylalanine-modified folic acid through a succinic acid linker. The modified polymer conjugate is configured for targeting folate receptors overexpressed on cancer cells. The phenylalanine conjugation enhances binding affinity of folic acid to folate receptors, and the methoxy polyethylene glycol modification improves solubility, stability, and pharmacokinetic performance. A method of synthesizing the modified polymer conjugate is also provided, comprising conjugating folic acid with phenylalanine to form a phenylalanine-modified folic acid, activating methoxy polyethylene glycol with succinic anhydride to form an mPEG-acid, and conjugating the phenylalanine-modified folic acid with the mPEG-acid.
Disclaimer: Curated by HT Syndication.
