MUMBAI, India, Sept. 22 -- Intellectual Property India has published a patent application (202617074710 A) filed by Genzyme Corporation; and Sunnybrook Research Institute on June 16, 2026, for Methods For Fus-Based Delivery Of Viral Particles To The Brain.
Inventors include Aubert, Isabelle; Elmer, Bradford Miller; Hynynen, Kullervo; Kofoed, Rikke H.; and Mueller, Christian.
The application for the patent was published on September 18, 2026, under issue no. 38/2026.
Abstract: Provided herein are methods to treat various neurodegenerative disorders comprising delivering a viral particles to the whole brain, including both superficial and deep structures. In some aspects, the viral particles are administered at low dose levels to the CSF, in conjunction with microbubbles followed by application of focused ultrasound (FUS) to a region of interest of the brain, thereby causing entry of the viral particles to the brain.
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