MUMBAI, India, Nov. 2 -- Intellectual Property India has published a patent application (202617092782 A) filed by Amgen Inc. on July 30, 2026, for Methods And Systems For Viscosity Prediction And Protein Engineering.
Inventors include Jain, Mani; Jia, Lei; and Estes, Bram.
The application for the patent was published on October 30, 2026, under issue no. 44/2026.
Abstract: A computer-implemented method for generating one or more modified amino acid sequences comprises obtaining, via one or more processors, one or more candidate amino acid sequences and characteristic data associated with the one or more candidate amino acid sequences; classifying, via the one or more processors, the one or more candidate amino acid sequences into a first set of high-viscous amino acid sequences and a second set of low-viscous amino acid sequences using a predictive model, the classifying comprising: calculating one or more viscosity predictions based on the one or more candidate amino acid sequences and the obtained characteristic data; and determining the first set of high-viscous amino acid sequences and the second set of low-viscous amino acid sequences based on the one or more viscosity predictions and a predetermined viscosity threshold, wherein the first set of high-viscous amino acid sequences comprises at least one candidate amino acid sequence; and generating, via the one or more processors, the one or more modified amino acid sequences based on the first set of high-viscous amino acid sequences using a generative model, wherein at least one of the one or more modified amino acid sequences has a viscosity prediction lower than the predetermined viscosity threshold.
Disclaimer: Curated by HT Syndication.
