MUMBAI, India, June 26 -- Intellectual Property India has published a patent application (202617032022 A) filed by Grail, Inc. on March 17, 2026, for Methods And Compositions For Analysis Of Cell-Free Biomarkers.

Inventors include Burkhardt, David H.; Larson, Matthew H.; Bala, Ruth E. Mauntz; Mesirov, Samuel D.; Su, Kenong; and Yakym, Christopher-James A. V..

The application for the patent was published on June 19, 2026, under issue no. 25/2026.

Abstract: In various aspects, the present disclosure provides methods for detection of various cancer types, comprising measuring the level of target molecules in a sample. In some embodiments, the one or more target molecules include a cell-free DNA (cfDNA) from a plurality of different target genomic regions that are differentially methylated in at least one of a plurality of cancer, and a plurality of different polypeptides that are differentially expressed in at least one of the plurality of cancer types. Methods for training a classifier for detecting target molecules from a cancer are also provided.

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