MUMBAI, India, Aug. 17 -- Intellectual Property India has published a patent application (202617056337 A) filed by Nanovation Therapeutics Inc. on May 04, 2026, for Method Of Delivery Of Dna Or Rna Cargo Using Unshielded Lipid Nanoparticles.
Inventors include Kurek, Daniel; Witzigmann, Dominik; and Kulkarni, Jayesh.
The application for the patent was published on August 14, 2026, under issue no. 33/2026.
Abstract: The present disclosure provides unshielded lipid nanoparticles and a process that enables the production of such unshielded lipid nanoparticles, thereby overcoming previous challenges of making particles without causing aggregation thereof. The lipid nanoparticles comprise a nucleic acid cargo molecule; a sterol or a derivative thereof present at a content of at least 12 mol%; a neutral lipid, such as a phospholipid having a choline head group present at a content of between 22 mol% and 65 mol%; and an ionizable cationic amino lipid present at a content of between 15 mol% and 45 mol%; wherein the lipid nanoparticle is non-sterically stabilized with a hydrophilic polymer-lipid conjugate, or otherwise unshielded and wherein each mol% content is relative to total lipid present in the lipid nanoparticle.
Disclaimer: Curated by HT Syndication.
