MUMBAI, India, Sept. 22 -- Intellectual Property India has published a patent application (202617077513 A) filed by Cytiva Bioprocess R&d Ab on June 23, 2026, for Method For Separating Nucleic Acid Molecules.
Inventors include Blom, Hans; Marx, Lisa; Guterstam, Peter; Hagman, Linda; and Aberg, Simon.
The application for the patent was published on September 18, 2026, under issue no. 38/2026.
Abstract: The present invention provides a method (100) for separating a single-stranded nucleic acid molecule from one or more impurities, the method comprising: adding (110) a feed comprising the single-stranded nucleic acid molecule and one or more impurities to a chromatography medium comprising a matrix material functionalised with a hydrophobic ligand comprising an amine-derived aromatic group, and eluting (120) the single-stranded nucleic acid molecule from the chromatography medium. Further provided is the use of a chromatography medium for purification of a single-stranded nucleic acid molecule, wherein the chromatography medium comprises a matrix material functionalised with a hydrophobic ligand comprising an amine- derived aromatic group, as well as the use of a chromatography device for the purification of a single-stranded nucleic acid molecule, wherein the chromatography device comprises a chromatography medium for purification of a single-stranded nucleic acid molecule, wherein the chromatography medium comprises a matrix material functionalised with a hydrophobic ligand comprising an amine-derived aromatic group.
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