MUMBAI, India, June 30 -- Intellectual Property India has published a patent application (202418030870 A) filed by Meso Scale Technologies, LLC. on April 17, 2024, for Method And Instrument For Reducing Crosstalk Between Ccd Measurements.

Inventors include Krivoy, Gary, I.; Zimmerman, Cecilia; Vanderdarl, Jules; Kovacs, Sandor; Leimkuehler, Aaron; Tabakin, Leo; Willoughby, Jon; Kochar, Manish Filed On; and Clinton, Charles, M..

The application for the patent was published on June 26, 2026, under issue no. 26/2026.

Abstract: A method and instrument for reducing crosstalk between measurements of a plurality of analytes in an assay plate performed by a ccd camera are disclosed. The method comprises: measuring the plurality of analytes with the CCD camera, the CCD camera including a CCD, an analog front end circuit, and an analog to digital circuit and being coupled to a focusing system and a plate carriage system configured to locate the assay plate to facilitate measurement of the plurality of analytes; receiving, via the analog front end circuit, a readout signal from the serial register of the CCD, wherein receiving the readout signal includes: transferring the readout signal from the serial register to the analog to digital circuit to generate a first image data point,resetting fully, via a reference level clamp circuit having a time constant, a reference level of the analog front end circuit, transferring the readout signal from the serial register to the analog to digital circuit to generate a second image data point.

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