MUMBAI, India, July 24 -- Intellectual Property India has published a patent application (202647086175 A) filed by Idorsia Pharmaceuticals Ltd on July 14, 2026, for Macrocyclic Orexin Agonists.
Inventors include Bezencon, Olivier; Chevillard, Florent; Hell, Sandrine; Peters, Jens-Uwe; Pozzi, Davide; Siegrist, Romain Number; and Surivet, Jean-Philippe.
The application for the patent was published on July 17, 2026, under issue no. 29/2026.
Abstract: The present invention relates to aryl thiol macrocycles of Formula (I) wherein R1, R2, RA1, X1, X2, X3, X4, L, X5, and Ring A are as described in the description, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more compounds of Formula (I), and their use as agonists of the orexin-2 receptor.
Disclaimer: Curated by HT Syndication.
