MUMBAI, India, Sept. 28 -- Intellectual Property India has published a patent application (202511022100 A) filed by Council Of Scientific And Industrial Research, An Indian on March 11, 2025, for Light-Induced Selective Bridged Etherification Of Bicyclic Hexahydro Indolo[4,3-Fg]quinolin Alkaloid Analogue Through Continuous Flow Systems.

Inventors include Chada Raji Reddy; Ajay Kumar Singh; Mounika Kukudala; Abhilash Rana; and Amol Dnyandev Patil.

The application for the patent was published on September 25, 2026, under issue no. 39/2026.

Abstract: The present invention relates to continuous flow synthesis of substituted ergot alkaloids and their analogs of general Formula 1 used for the treatment of symptoms associated with cerebrovascular abnormalities and vascular disorders such as cerebral thrombosis and atherosclerosis, arterial blockages in the limbs, Raynaud’s disease, vascular migraines, and retinopathy drug. This invention further extended to the synthesis of nicergoline utilizing sunlight as a light source in the first step of synthesis Formula 1.

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