MUMBAI, India, June 26 -- Intellectual Property India has published a patent application (202527094216 A) filed by Zhejiang Ausun Pharmaceutical Co. , Ltd. on September 30, 2025, for Intermediate Compounds Of Pilocarpine And Preparation Method Therefor.
Inventors include Guo, Jiajia; Dai, Chunguang; Zhang, Lirong; Yu, Guanneng; Zhang, Shengkang; and Zheng, Zhiguo.
The application for the patent was published on June 19, 2026, under issue no. 25/2026.
Abstract: The present invention relates to intermediate compounds of pilocarpine and a preparation method therefor. In particular, the present invention relates to compounds of formula V and formula I for preparing pilocarpine and a preparation method therefor. In the method, a compound of formula II is used as a raw material, and a compound of formula V is obtained after halogenation hydrolysis, oxidation and substitution reactions; and then the compound of formula V is subjected to a reduction reaction and a ring-forming reaction to obtain the compound of formula I. The preparation method of the present invention has the advantages of mild reaction conditions, a simple reaction process, a high total yield, a high purity, etc., and is very suitable for industrial production.
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