MUMBAI, India, July 31 -- Intellectual Property India has published a patent application (202411096005 A) filed by Lovely Professional University on December 05, 2024, for Instantaneous Microsphere Production System For Sustained Ophthalmic Drug Delivery.

Inventor includes Ramanjireddy Tatiparthi.

The application for the patent was published on July 24, 2026, under issue no. 30/2026.

Abstract: The present invention relates to an instantaneous microsphere production system specifically designed for sustained ophthalmic drug delivery. The system comprises a production unit equipped with a mixing chamber for combining formulation components such as EUDRAGIT RSPO, HPMC K4M, and EC, which are selected for their biocompatibility and ability to form stable matrices. A drug encapsulation module is included to encapsulate an active pharmaceutical ingredient within the microspheres, ensuring stability and efficacy by preventing acidic degradation. The system employs a control system utilizing a full factorial design to optimize formulation variables, achieving a desired drug release profile characterized by non-Fickian transport diffusion mechanisms and zero-order kinetic release. This configuration allows for a controlled and sustained release of the drug over an extended period, maintaining therapeutic drug levels. The production unit is further configured for pilot-scale production, ensuring scalability and compliance with USP specifications. Dated this …. Day of November, 2024 Dr. Monica Gulati Registrar Lovely Professional University

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