MUMBAI, India, Nov. 2 -- Intellectual Property India has published a patent application (202541101837 A) filed by Indian Institute Of Technology Madras Iit Madras on October 22, 2025, for In Situ Mineralized Hydrogel Composite And Microfluidic Platform For Simulating Bone Metastasis.
Inventors include Shantanu Pradhan; Ramya Dhandapani; and Kadambari Sathyanarayanan.
The application for the patent was published on October 30, 2026, under issue no. 44/2026.
Abstract: ABSTRACT IN SITU MINERALIZED HYDROGEL COMPOSITE AND MICROFLUIDIC PLATFORM FOR SIMULATING BONE METASTASIS The present disclosure provides a process for preparing an in situ mineralized hydrogel composite and an in situ mineralized hydrogel composite obtainable by said process, suitable for use as a bone-mimetic extracellular matrix for encapsulating osteogenic lineage cells. The present disclosure also provides a system (700) and a method for synthesizing said in situ mineralized hydrogel composite in the form of microspheres, as well as a microfluidic device (600) configured for co-culturing different cell types, which is suitable for simulating cancer cell invasion, bone metastasis, chemotherapy-induced bone metastasis, and drug screening applications. [Figure 6B, 7C]
Disclaimer: Curated by HT Syndication.
