MUMBAI, India, June 24 -- Intellectual Property India has published a patent application (202544098385 A) filed by F. I. S. Fabbrica Italiana Sintetici S. P. A. on October 13, 2025, for Improved Process For The Preparation Of Cariprazine.
Inventors include De Poli Matteo; Tyler Andrew; and Marcazzan Gabriele.
The application for the patent was published on June 12, 2026, under issue no. 24/2026.
Abstract: IMPROVED PROCESS FOR THE PREPARATION OF CARIPRAZINE Object of the present invention is an improved process for the preparation of Cariprazine compound of formula (1): (1), comprising the step of adding a base to a mixture comprising phosgene or a carbonic acid derivative and amino piperazine compound of formula (3): (3) in a salt form, to give an isocyanate compound of formula (2): (2) and/or compound of formula (11): (11).
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