MUMBAI, India, July 13 -- Intellectual Property India has published a patent application (202617073300 A) filed by Capstan Therapeutics, Inc. on June 12, 2026, for Humanized Anti-Cd8 Antibodies And Uses Thereof.
Inventors include Nguyen, Duy; Presta, Leonard, G.; Martinko, Alexander; Yong, Qian-Chen Number; and Sievers, Stuart, Aaron.
The application for the patent was published on July 10, 2026, under issue no. 28/2026.
Abstract: The present disclosure provides humanized antibodies and antigen binding domains thereof that bind CD8a and other antibody formats comprising these antigen binding domains, their use as a targeting moiety on lipid nanoparticles (tLNP) to deliver a therapeutic payload (such as a nucleic acid molecule) or other types of payloads. The present disclosure further relates to pharmaceutical compositions comprising the humanized anti-CD8a antibodies and CD8-targeted tLNP encapsulating a payload.
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