MUMBAI, India, Aug. 31 -- Intellectual Property India has published a patent application (202621085090 A) filed by Dr. Khan Dureshahwar Riyaz Ali; Pratiksha Gajanan Harale; and Dr. Maria Abbasi Saifee on July 11, 2026, for Herbal Niosomal Transdermal Patch For Targeted-Antileukemic Therapy In Acute Myeloid Leukaemia And A Process Thereof.
Inventors include Dr. Khan Dureshahwar Riyaz Ali; Pratiksha Gajanan Harale; and Dr. Maria Abbasi Saifee.
The application for the patent was published on August 28, 2026, under issue no. 35/2026.
Abstract: The present invention relates to a process for preparing an herbal niosomal transdermal patch of Cuminaldehyde specifically formulated for targeted antileukemic therapy in Acute Myeloid Leukemia. The process involves an initial phase of synthesizing niosomal vesicles through the controlled injection of an organic mixture—comprising Span 60, Phosphatidylcholine, and Cuminaldehyde—into a heated aqueous phase at a flow rate of 0.25 mL/minute. This stage facilitates the self-assembly of surfactant molecules and the instantaneous vaporization of the ether solvent. Subsequently, the resulting niosomal suspension is integrated into a dual-polymer matrix consisting of Polyvinylpyrrolidone (PVP) K30 and Hydroxypropyl Methylcellulose. To ensure flexibility and structural integrity, propylene glycol is incorporated as a plasticizer. The final mixture is cast onto a level surface and dried at temperatures up to 50°C for 24 to 48 hours. The resulting medicated film provides a stable, controlled-release mechanism for the herbal active ingredient via the transdermal route.
Disclaimer: Curated by HT Syndication.
