MUMBAI, India, Aug. 10 -- Intellectual Property India has published a patent application (202641085945 A) filed by Srm Dental College Ramapuram on July 14, 2026, for Herbal Mouth Refreshing Spary Composition Comprising Ethanolic Fruit Extract Of Morinda Citrifolia For Oral Health Management.
Inventors include Dr Surekha Ramachandran; Dr S Nirmala; Ms Darshini B; Ms Hahni R; and Ms Shreya V.
The application for the patent was published on July 31, 2026, under issue no. 31/2026.
Abstract: TITLE OF THE INVENTION Herbal Mouth-Refreshing Spray Composition Comprising Ethanolic Fruit Extract of Morinda Citrifolia for Oral Health Management ABSTRACT OF THE INVENTION The present invention discloses a mouth-refreshing spray incorporating an ethanolic fruit extract of Morinda citrifolia (noni) for oral care. The ethanolic extract, richest in flavonoids, alkaloids, anThraquinones, polyphenols, saponins, steroids, and terpenoids, was incorporated at 3% (Fl), 5% (F2), and 10% (F3) into a biocompatible spray base containing xylitol, propylene glycol, and vitamin E. All formulations exhibited clarity, uniform spray pattern, and a physiologically compatible pH of 6.2-7.4. Antioxidant evaluation yielded ICso values of204.06 ± 4.25 gg/mL (DPPH), 229.22 ± 5.17 gg/rnL (H2O2), and 227.01 ± 4.98 gg/mL (NO). The F3 formulation demonstrated superior antimicrobial activity against Streptococcus miitans (ZOI; 20 mm; MIC: 0.156 mg/mL) and Candida albicans (ZOI: 11 mm; MIC: 0.039 mg/mL). Twelve-week stability testing confirmed retention of appearance, pH, spray uniformity, and antimicrobial efficacy. The invention offers a safe, natural, and effective alternative to synthetic oral hygiene sprays, suitable for routine clinical application.
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