MUMBAI, India, June 30 -- Intellectual Property India has published a patent application (202617059275 A) filed by Providence Therapeutics Holdings Inc. on May 09, 2026, for Glutamic Acid-Based Lipids, Lipid Nanoparticle Containing Glutamic Acid-Based Lipids, And Formulations Thereof.
Inventors include Gopalakrishna Panicker, Rajesh Krishnan; Karpov, Yury; Jain, Aarushi; Martin Orozco, Natalia; and Ponduri, Rajasekhar.
The application for the patent was published on June 26, 2026, under issue no. 26/2026.
Abstract: Provided is a glutamic or glutaric acid-based ionizable lipid compound of Formula (I) or a pharmaceutically acceptable salt thereof. The compound can be used to obtain lipid nanoparticles. In some embodiments, the lipid nanoparticle can comprise (a) from about 40 to about 100 mol % of the compound of Formula (I); (b) from 0 to about 20 mol % of a neutral lipid; (c) from 0 to about 50 mol % of a helper lipid; (d) from 0 to about 5 mol % of a polymer-conjugated lipid; and (e) from 0 to about 10 mol % of a hydrophobic component; wherein the mol % are based on the total lipids present in the nanoparticle. In some embodiments, the ionizable lipid compound is a glutamic acid-based ionizable lipid compound.
Disclaimer: Curated by HT Syndication.
