MUMBAI, India, Sept. 28 -- Intellectual Property India has published a patent application (202418054852 A) filed by President And Fellows Of Harvard College on July 18, 2024, for Gene Editing Of Pcsk9.
Inventors include Maianti, Juan, Pablo; and Liu, David, R..
The application for the patent was published on September 25, 2026, under issue no. 39/2026.
Abstract: Provided herein are systems, compositions, and methods of introducing loss-offunction mutations in to protein factors involved in the LDL-R-mediated cholesterol clearance pathway, e.g., PCSK9, APOC3, LDL-R, or IDOL. Loss-of-function mutations may be introduced using a CRISPR/Cas9-based nucleobase editor described in. Further provided herein are compositions and methods of treating conditions related to high circulating cholesterol levels.
Disclaimer: Curated by HT Syndication.
