MUMBAI, India, Oct. 26 -- Intellectual Property India has published a patent application (202611106902 A) filed by Panipat Institute Of Engineering And Technology Piet on September 04, 2026, for Gastroretentive Floating Pulsatile Pharmaceutical Tablet With A Gas-Generating Layer.
Inventor includes Dr. Parveen Kumar Goyal.
The application for the patent was published on October 23, 2026, under issue no. 43/2026.
Abstract: [063] The present invention relates to a gastroretentive floating pulsatile pharmaceutical tablet configured to provide temporally coordinated gastric buoyancy and delayed pulse release of an active pharmaceutical ingredient. The tablet comprises a drug-containing layer, a gas-generating layer comprising at least one physiologically acceptable gas-generating agent and a swellable gas-retaining polymer, and at least one programmable barrier layer positioned to regulate access of gastric fluid to the drug-containing layer. Upon exposure to gastric fluid, the gas-generating layer hydrates and generates gas that is entrapped within a swollen polymeric structure to reduce the apparent density of the tablet and establish buoyancy. During a predetermined lag period, the programmable barrier restricts substantial release of the active pharmaceutical ingredient. Following swelling, erosion, dissolution, rupture, increased permeability, or mechanical transition of the barrier, gastric fluid gains increased access to the drug-containing layer, thereby producing accelerated pulse release. The layered architecture enables buoyancy generation and release timing to be independently adjusted and provides a gastroretentive platform for time-programmed oral drug delivery. Accompanied Drawing [FIGS. 1-2]
Disclaimer: Curated by HT Syndication.
