MUMBAI, India, July 13 -- Intellectual Property India has published a patent application (202418057074 A) filed by Spogen Biotech Inc. on July 26, 2024, for Fusion Proteins, Recombinant Bacteria, And Methods For Using Recombinant Bacteria.
Inventors include Thompson, Brian; and Siegel, Ashley.
The application for the patent was published on July 10, 2026, under issue no. 28/2026.
Abstract: Fusion proteins containing a targeting sequence, an exosporium protein, or an exosporium protein fragment that targets the fusion protein to the exosporium of a Bacillus cereus family member are provided. Recombinant Bacillus cereus family members expressing such fusion proteins are also provided. Genetically inactivated Bacillus cereus family members and recombinant Bacillus cereus family members that overexpress exosporium proteins are also provided. Seeds coated with the recombinant Bacillus cereus family members and methods for using the recombinant Bacillus cereus family members (e.g., for stimulating plant growth) are also provided. Various modifiations of the recombinant Bacillus cereus family members that express the fusion proteins are further provided. Fusion proteins comprising a spore coat protein and a protein or peptide of interest, recombinant bacteria that express such fusion proteins, seeds coated with such recombinant bacteria, and methods for using such recombinant bacteria (e.g., for stimulating plant growth) are also provided.
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