MUMBAI, India, June 22 -- Intellectual Property India has published a patent application (202641070676 A) filed by Ranganathan Srinivasan; Jayaramakani. N; Punithavalli. S; Madhanprasath. G; Hariharan. V; Prasanna Badmanaban. Km; Dr. R. Saravanan; Kanakambigai. M; Hari Nandhini. A; and Dr. R. Devi on June 06, 2026, for Formulation And Evaluation Of An Allium Cepa Based Wound Healing Gel.
Inventors include Ranganathan Srinivasan; Jayaramakani. N; Punithavalli. S; Madhanprasath. G; Hariharan. V; Prasanna Badmanaban. Km; Dr. R. Saravanan; Kanakambigai. M; Hari Nandhini. A; and Dr. R. Devi.
The application for the patent was published on June 12, 2026, under issue no. 24/2026.
Abstract: In order to create a stable, safe, and effective topical preparation with enhanced therapeutic activity, the present invention relates to the formulation and evaluation of a herbal wound healing gel containing Allium cepa extract as the primary active ingredient for the effective treatment and management of wounds and skin injuries. Onion extract has significant antimicrobial, anti-inflammatory, antioxidant, and tissue regenerative properties that help speed up the wound site by lowering inflammation, oxidative stress, and microbial growth. In order to create a stable, safe, and efficient topical treatment with increased therapeutic efficacy, the formulation was created utilizing appropriate pharmaceutical and herbal excipients. By lowering microbial growth, inflammation, and oxidative stress at the wound site, onion extract's potent antibacterial, anti-inflammatory, antioxidant, and tissue-regenerative qualities assist hasten the healing process. In order to achieve desired physicochemical features such good homogeneity, smooth texture, acceptable pH, viscosity, spreadability, and extrudability for convenient topical administration, the produced gel was synthesized utilizing the correct gelling agents, preservatives, humectants, and stabilizers. Physical appearance, pH determination, viscosity measurement, spreadability study, stability testing, in-vitro drug diffusion investigation, and antibacterial effectiveness against common wound pathogens were among the evaluation criteria applied to the created formulation. The outcomes showed that the herbal gel had good stability, controlled release properties, and strong antibacterial activity with enhanced potential for wound healing. With fewer side effects and an enhanced safety profile, the invention offers a natural, affordable, and patient-friendly substitute for traditional synthetic wound healing composition. For the treatment of cuts, burns, wounds, and other skin-related injuries, the prepared herbal wound healing gel has prospective uses in the pharmaceutical and cosmeceutical industries.
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