MUMBAI, India, Sept. 22 -- Intellectual Property India has published a patent application (202541021615 A) filed by Biodimension Technology Private Limited on March 11, 2025, for Enhanced Mechanical Resilience Of Epithelial Models Via Crosslinked Coatings.
Inventors include Manojkumar Sampathkumar; Chiragkumar Rasbhara; Dr. Dhara Jajal; and Mohanya Kumaravel.
The application for the patent was published on September 18, 2026, under issue no. 38/2026.
Abstract: ABSTRACT Enhanced mechanical resilience of epithelial models via crosslinked coatings The present invention is related to a method (100) for synthesizing a bio- fabricated epithelial tissue model comprising preparing a coating solution comprising one or more biocompatible polymers and adding onto a substrate suitable for culturing epithelial cells (101); crosslinking of coated transwells with one or more crosslinkers (102); applying the crosslinkers onto substrate coated with coating material suitable for culturing epithelial cells (103); and culturing epithelial cells on substrate coated and crosslinked to form a biofabricated epithelial tissue model (104) such that the crosslinker forms covalent bonds with free amino groups of the polymer(s) and enhance the mechanical strength, stability, and resistance to enzymatic degradation of the coating material.
Disclaimer: Curated by HT Syndication.
