MUMBAI, India, Nov. 2 -- Intellectual Property India has published a patent application (202611097679 A) filed by Neera Raghav; Kurukshetra University Kurukshetra; and Chanchal Vashisth on August 12, 2026, for Dual Protease Inhibitor Compositions Comprising Nitro-Substituted Cinnamaldehyde-Aniline Schiff Bases.
Inventors include Neera Raghav; and Chanchal Vashisth.
The application for the patent was published on October 30, 2026, under issue no. 44/2026.
Abstract: The present invention discloses dual-action protease inhibitors designed to address the limitations of existing prior art by significantly expanding target inhibition capabilities against pepsin and cathepsin B enzymes. The active agents provided in Formula F1-F3 represent unsubstituted, 2-nitro and 3-nitro substituted cinnamaldehyde-aniline schiff bases. The structural designs as disclosed marked a valuable innovative optimization in the enzyme-inhibitor discovery having a dual- target inhibitory efficiency establishing high-performance profiles in balancing multiple proteolytic pathways.
Disclaimer: Curated by HT Syndication.