MUMBAI, India, July 24 -- Intellectual Property India has published a patent application (202418072539 A) filed by Rubedo Life Sciences, Inc. on September 25, 2024, for Drug Conjugates Of Sugar Derivatives And Uses Thereof As Senolytic Agents.
Inventors include Quarta, Marco; Gallop, Mark A.; Jasper, Jeffrey R.; Keitz, Paul; and Bergnes, Gus Number.
The application for the patent was published on July 17, 2026, under issue no. 29/2026.
Abstract: Provided herein are agents and methods for selectively killing senescent cells that are associated with numerous pathologies and diseases, including age-related pathologies and diseases. As disclosed herein, senescent cell-associated diseases and disorders may be treated or prevented by administering at least one senolytic agent or pharmaceutical compositions thereof. The senescent cell- associated diseases or disorders treated or prevented by the agents and methods described herein include, but are not limited to, cardiovascular diseases or disorders, cardiovascular diseases and disorders associated with arteriosclerosis, such as atherosclerosis, idiopathic pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD), osteoarthritis, inflammatory or autoimmune diseases or disorders, pulmonary diseases or disorders, neurological diseases or disorders, dermatological diseases or disorders, chemotherapeutic side effects, radiotherapy side effects, metastasis and metabolic diseases.
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