MUMBAI, India, Aug. 24 -- Intellectual Property India has published a patent application (202621080930 A) filed by Symbiosis International Deemed University on June 30, 2026, for Digital Twin Based System And Method For Personalized Lung Cancer Treatment In Metaverse Environments.

Inventors include Yash Khadgi; Rudrakshi Bhandekar; Ananya Marghade; and Dr. Priya Dasarwar.

The application for the patent was published on August 21, 2026, under issue no. 34/2026.

Abstract: ABSTRACT DIGITAL TWIN BASED SYSTEM AND METHOD FOR PERSONALIZED LUNG CANCER TREATMENT IN METAVERSE ENVIRONMENTS The present invention provides a digital twin based system (100) and method for personalized lung cancer treatment simulation in a metaverse environment. The system (100) comprises a data acquisition and preprocessing module (110) for processing DICOM CT images with Hounsfield Unit conversion and isotropic resampling, a segmentation extraction module (120) for extracting gross tumor volume masks from DICOM SEG objects, a three dimensional mesh generation module (130) employing Marching Cubes algorithm and Laplacian smoothing, a radiomic feature extraction module (140) computing over one hundred quantitative features, a machine learning inference module (150) using Random Forest classifiers for risk stratification and survival prediction, a treatment simulation engine (160) implementing Gompertz differential growth equation with treatment specific kill rates for radiotherapy, chemotherapy, immunotherapy, and surgery, a toxicity modeling module (170) with cyclic Gaussian pulse and linear accumulation functions, and a metaverse visualization interface (180) providing immersive three dimensional rendering. [

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