MUMBAI, India, Sept. 22 -- Intellectual Property India has published a patent application (202611088832 A) filed by Uttaranchal University on July 21, 2026, for Development Of A Novel Polyherbal Formulation Derived From Methanolic Leaf Extracts Of Medicinally Important Ficus Species With Bactericidal Potential.

Inventors include Rahul Gaur; Chandra Kanta; and Ajay Singh.

The application for the patent was published on September 18, 2026, under issue no. 38/2026.

Abstract: The present invention relates to the development and evaluation of a novel polyherbal bactericidal formulation derived from methanolic leaf extracts of medicinally important Ficus species, namely Ficus benghalensis, Ficus benjamina, Ficus racemosa, Ficus religiosa, and Ficus virens. The invention focuses on the preparation of six different polyherbal formulations (F1-F6) using varying proportions of methanolic leaf extracts to enhance synergistic antibacterial activity against selected pathogenic bacterial strains, including Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis, and Bacillus cereus. The methanolic leaf extracts were prepared using Soxhlet extraction and subsequently combined in different ratios for formulation development. Antibacterial activity of the developed formulations was evaluated using agar well diffusion assay, minimum inhibitory concentration (MIC), and bactericidal potential through minimum bactericidal concentration (MBC) analyses. The obtained results demonstrated broad-spectrum antibacterial efficacy of the developed formulations against both Gram-positive and Gram-negative bacteria. Among the tested formulations, formulation F5 exhibited the highest antibacterial activity, followed by F2, F6, F4, F3, and F1, respectively, indicating enhanced synergistic interaction among phytochemicals present in the selected Ficus species. The developed polyherbal formulations contain diverse bioactive compounds, including phenolics, flavonoids, tannins, alkaloids, glycosides, and terpenoids, responsible for bactericidal effects. The invention provides a plant-based, eco-friendly, biodegradable, cost- effective, and sustainable alternative to conventional synthetic antibacterial agents with potential applications in pharmaceutical, herbal healthcare, and natural antimicrobial industries.

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